Israeli strikes killed at least 12 Palestinians in the Gaza Strip, mostly women and children, officials said Wednesday, as the nearly 15-month war ground on into the new year with no end in sight.

One strike hit a home in the Jabaliya area of northern Gaza, the most isolated and heavily destroyed part of the territory, where Israel has been waging a major operation since early October. Gaza's Health Ministry said seven people were killed, including a woman and four children, and at least a dozen other people were wounded.