A novel FN1 gene variant slashes Alzheimer’s risk by 70%, offering hope for improved treatments. Columbia University researchers, scrutinizing individuals with the APOEe4 gene, identified a protective FN1 variant, suggesting a counterbalance to APOEe4’s Alzheimer’s risk. Genome sequencing of 10,763 subjects unveiled FN1’s role in regulating brain fibronectin levels, vital for the blood-brain barrier’s integrity.…

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